Recently in building aerodynamics the school of computer simulation of wind influence on the building became urgent. The widespread high building construction plays significant role here. In this article the genesis of multiblock calculation methodology for modeling wind influence on the high buildings is presented. The methodology of calculation of wind influence on the high-altitude constructions, based on using multibank overlapping grids of various scales is developed. The methodology is verified on the test problem of a flow around a cube with short circuit with the help of model of shear stress transport. Periodic character of local and integrated wind loadings on a high-altitude building is analyzed.