Fibres improve concrete properties that can be used to solve the problem of limited resources. This research includes the numerical comparison of high-performance concrete (HPC) and high-performance steel fibre reinforced concrete (HPSFRC) behaviour. The numerical comparison is based on the analyse of stress-strain curves of considered materials. The limits of rational use of HPC and high-performance steel fibre reinforced concrete HPSFRC have been determined based on typical stress resultants values acting in the elements of multi-storey buildings. The values of stress resultants were determined by the numerical model, which was developed by the software ANSYS. Interaction diagrams of bending moments and axial forces M-N for elements subjected to combined action of compression and bending with different cross-sections have been developed. Curves for slabs of two material types that describe the allowable values of distributed load at different spans of the slabs are created. The resulting curves are analysed together with the actual stress resultants of the elements concerned from the numerical model. Taking into account distribution of stress resultants in the elements of multi-storey buildings, it was stated that the elements subjected to flexure are preferable field of application for HPSFRC. Ultimate value of bending moment is higher for HPSFRC comparing to HPC with the same parameters of cross-section. It is found that it is more rational to use HPSFRC for columns in the first eight floors. HPSFRC should be preferred as a material of the lower and middle floors of multi-storey buildings and of the walls of all floors in the case of column spacing more than 8 m, and for the slabs with span interval 6–12 m.