This research paper presents a comprehensive investigation on soil-structure interaction, combining theoretical research and in-situ observations. Detailed calculations and a thorough comparison of the results with long-term settlement observations are provided, accompanied by the validation of the proposed elasto-visco-plastic soil model through rigorous calculations. Real-world examples showcasing the application of design methods incorporating soil-structure interaction calculations in civil and industrial engineering, as well as in the reinforcement and restoration of historical buildings, are also presented. The study reveals that neglecting the spatial behavior of soil leads to significant underestimation of stresses in structures. For buildings on spread footings, the underestimation can range from 150% to 400%, while for buildings on pile foundations, it can be as high as 200% to 900%. Furthermore, an innovative architectural solution employed in a high-rise building successfully mitigated settlement issues by utilizing longer piles. The calculated settlement was reduced to 60 mm, and the actual settlement observed three years after construction was only 32 mm, indicating the effectiveness of the implemented solution. By emphasizing the importance of soil-structure interaction calculations, this research fosters a unified approach among various stakeholders involved in construction design. The findings and methodologies presented in this paper hold great potential to significantly enhance the field of geotechnical engineering, enabling more accurate and effective design approaches for various structures and applications.